Results 1 - 34 of 34 Courses

Microbiology and Immunology
Department of Microbiology & Immunology, College of Medicine

KEY TO COURSE
DESCRIPTIONS
Microbiology and Immunology >

For details on the B.Sc. in Microbiology see the College of Arts & Science section.

UNDERGRADUATE DEGREE COURSES
MICR 214.3
Basic and Medical Microbiology
1(3L-3P)
Prerequisite(s): BIOL 110; CHEM 112. Students intending to major in Microbiology must take BIOC 200 concurrently.

An introduction to the structure, physiology, and genetics of micro-organisms, with special consideration given to bacteria and viruses of medical importance and their role in human disease.

Note: Laboratories emphasize techniques used in the study of micro-organisms. Students with credit for APMC 212 may not take this course for credit.

MICR 216.3
Introductory Prokaryotic Genetics and Physiology
2(3L/3P)
Prerequisite(s): MICR 214 or APMC 212; BIOC 200.

Introduces the metabolic and genetic properties of bacterial cells. Topics include bacterial growth and culture systems, key metabolic pathways and their regulation, nutrient transport systems, organization of genetic material, regulation of bacterial and viral gene expression and genetic exchange mechanisms. Students will appreciate the central role of bacteria in modern biotechnology. Laboratories illustrate concepts developed in the lectures.

MICR 224.3
Microbiology for Pharmacists
2(3L-3P)
Prerequisite(s): BIOL 110; CHEM 111. Restricted to students enrolled in the College of Pharmacy.

Introduces students to medically-important microorganisms including bacteria, viruses, fungi, and parasites. Topics include the structure and function of microorganisms, host-pathogen interactions, immunological principles, antimicrobial agents and resistance, infection control principles, and a representative survey of medically relevant microorganisms. Laboratory exercises stress the observation, growth, and safe handling of microorganisms.

Note: Replaces MICR 214 in the Pharmacy program (students who already have credit for MICR 214 will not be required to take MICR 224).

MICR 308.3
Medical Bacteriology
1(3L)
Prerequisite(s): APMC 212 or MICR 214; BIOC 200.

Considers the characteristics of bacterial agents of infectious disease in humans. Host-parasite interactions are emphasized with respect to pathogenesis and the innate immune response. The role of the laboratory in the control of infectious disease is discussed.

MICR 309.3
Medical Virology
2(3L)
Prerequisite(s): APMC 212 or MICR 214; BIOC 200.

The principles of animal virology are covered, including classification, cell-virus relationships, basic techniques in virology, transmission of viruses, and study of viral disease.

MICR 387.3 (Formerly 386)
Microbial Genetic Systems
1(3L/1T)
Prerequisite(s): MICR 214, 216; BIOL 211; BIOC 200.

Bacterial and bacteriophage genetic systems will be dissected with a view to understanding their genomes, gene regulation, replication, mutagenesis, repair, and recombination, and their practical use as tools for molecular genetics experimentation and biotechnology.

Note: Students with credit for MICR 386 may not take MICR 387 for credit.

MICR 390.3 (Formerly 395)
Laboratory Aspects of Microbiology I
1(3L/4P)
Prerequisite(s): MICR 214, 216; BIOC 200.

The principles and applications of techniques used in microbiology are covered with an emphasis on problem solving. Included are methods relating to safe handling, growth and identification of microbes and methods for studying virology and immunology.

Note: Intended primarily for Microbiology students. Others may be considered if space permits. For permission contact the Department of Microbiology and Immunology.

MICR 391.3 (Formerly 395)
Laboratory Aspects of Microbiology II
2(3L/4P)
Prerequisite(s): MICR 214 , 216; BIOC 200.

The principles and applications of techniques used in microbiology are covered with an emphasis on problem solving. Included are methods for studying microbial physiology and genetics, and basic methods of microbial gene manipulation. Students with credit for MICR 391 cannot receive credit for BIOC 311.

Note: Intended primarily for Microbiology students. Others may be considered if space permits. For permission contact the Department of Microbiology and Immunology.

MICR 416.3 (Formerly 215)
Microbial Physiology
2(3L)
Prerequisite(s): MICR 216; BIOC 200 (Students majoring in microbiology must also take BIOC 211 previously or concurrently).

Considers the structure and function of micro-organisms, the relationship between structure and function, mechanisms of cell division, composition of microbial cell walls and membranes, aerobic, fermentative, chemolithotrophic and photolithotrophic metabolism, and regulation of genes and metabolism.

Note: students with credit for MICR 215 may not take MICR 416 for credit.

MICR 417.3
Molecular Virology
1(3L)
Prerequisite(s): BIOC 200; MICR 214 or APMC 212.

Representative members of known animal virus families are used as models of biological events at a macromolecular level. Topics covered are virus purification and analysis methods, virus structure and self-assembly, virus genomes and genome expressions, virus proteins and their function, and virus-cell interactions during lytic, transforming, persistent and slow virus infections.

MICR 421.3
Principles of Immunology
1(3L)
Prerequisite(s): BIOC 200; MICR 214 or APMC 212.

Emphasizes the fundamental aspects of immunology dealing with the structure, genetics and function of antibody molecules, and the cellular and molecular regulation of immune responses. A portion is devoted to regulation of the immune response to tumours and particular parasites.

MICR 423.3
Immunopathogenesis of Microbial Infections
2(3L)
Prerequisite(s): MICR 421.

Explores microbial interactions with the host and its immune system. Various models of bacterial, viral and parasitic immunopathogenesis will be covered as well as intervention through vaccines or immune modulation.

MICR 425.3
Molecular Basis of Microbial Pathogenesis
2(3L)
Prerequisite(s): MICR 214, a course in genetics or molecular biology; or permission of the department.

Explores ways in which microbial pathogens interact with their hosts from a molecular and genetics perspective. Topics include: general pathogenic mechanisms of bacteria, viruses and parasites; bacterial virulence factors and their genetic regulation; molecular genetic approaches to studying pathogenesis; and various model systems which have been used to understand pathogenic mechanisms.

MICR 490.0
Seminar
1&2(1S)

In their final year, students in the Honours Microbiology program are required to present one departmental seminar and to attend all departmental seminars.

MICR 491.6 (Formerly 497)
Research Project in Microbiology
Prerequisite(s): Minimum cumulative average of 70% in those courses counting toward the microbiology requirement of an Honours Degree in Microbiology. Permission of department is required.

A research project is selected in consultation with a faculty supervisor in whose laboratory the research will be carried out. Students will become familiar with the scientific literature and the laboratory techniques pertinent to the project. Experimental work will be undertaken and data compiled and analyzed. To complete the research project, a written report will be tabled and a short oral presentation will be given to faculty and students.

Note: Intended primarily for those students majoring in microbiology who are considering a post-graduate degree in microbiology or another area of the life sciences.




Special Topics

These courses are offered occasionally by visiting faculty and in other special situations. Students interested in these courses should contact the department for more information.
MICR 398.3

1/2(3S)

MICR 399.6

1&2(3S)

MICR 498.3

1/2(3S)

MICR 499.6

1&2(3S)

GRADUATE COURSES
Department of Microbiology & Immunology, College of Graduate Studies & Research
MICR 716.3
Microbial Physiology
2(3L-1S)
Prerequisite(s): MICR 216; BIOC 200 or permission of the coordinator.

Molecular structures, functions and regulatory mechanisms relating to growth, membrane transport, metabolism, macromolecular synthesis and gene expression in microorganisms.

MICR 717.3
Molecular Virology
1(3L)

Representative members of known animal virus families are used as models of biological events at a macromolecular level. Topics are virus purification and analysis methods, virus structure and self-assembly, viral genomes and genome expression, virus proteins and their function, and virus-cell interactions during lytic, transforming, persistent and slow virus infections. For further graduate training in virology, see VTMC 833.

MICR 787.3
Microbial Genetics
1(3L)
Prerequisite(s): MICR 214, 216; BIOL 211; BIOC 200 or equivalent.

Bacterial and bacteriophage genetic systems will be discussed with a view to understanding their genomes, gene regulation, replication, mutagenesis, repair, and recombination, and their practical use as tools for molecular genetics experimentation and biotechnology.

Note: Not offered 2005-2006.

MICR 814.3
Advanced Microbial Physiology
1(3S)
Prerequisite(s): MICR 416 or MICR 716 or permission of the course coordinator.

Consideration of advanced topics and current research relating to molecular structures, functions and regulatory mechanisms in the growth, membrane transport, metabolism, macromolecular synthesis, chemotaxis and gene expression of microorganisms.

MICR 816.3
Genetic Analysis of Eukaryotic Microorganisms
1(3L)
Prerequisite(s): BIOL 211 and MICR 387 or permission of the instructor.

Review various biochemical, genetic and molecular biological approaches in the study of model unicellular eukaryotic microorganisms, primarily Saccharomyces yeasts. Emphasis will be on genome organization and manipulation, DNA metabolism, control of gene expression and cell cycle regulation. The complete yeast genome sequence and its application will be discussed. Experimental strategies developed in these lower eukaryotes for the study of other organisms will also be discussed.

MICR 820.3
DNA Repair and Mutagenesis
1(3L)
Prerequisite(s): BIOL 211 or MICR 216, BIOC 200 or equivalent, and permission of the instructor.

Explores the process of DNA damage, repair, mutagenesis and impacts on cell survival, molecular evolution and human diseases. Emphasis given to molecular, cellular, genetic and biochemical analysis of each repair pathway in various organisms. Students are expected to be familiar with the technologies and strategies used in the investigations.

MICR 821.3
Principles of Immunology
1(3L-1S)
Prerequisite(s): MICR 214 or APMC 212; BIOC 200; permission of the instructor.

Emphasizes the fundamental aspects of immunology dealing with the structure, genetics and function of antibody molecules, and the cellular and molecular regulation of immune responses. A portion is devoted to regulation of the immune response to tumors and particular parasites.

MICR 823.3
Immunopathogenesis of Microbial Infections
2(3L-3S)
Prerequisite(s): MICR 421 or equivalent.

Explores model systems to gain an understanding of how microbial infections are contained by the host's innate and cognate defense systems and how the activation of the cellular and molecular immune mechanisms contribute to pathology. Topics include basic mechanisms of immune-cell migration and inflammation, functions of microbe induced cytokines, microbe initiated inflammatory responses such as toxic shock syndrome and granulomas, microbe initiated autoimmune and immunodeficiency diseases and control of microbial infections by immunomodulation and vaccination.

MICR 825.3
Molecular Basis of Microbial Pathogenesis
2(3L)
Prerequisite(s): MICR 216 and a course in molecular genetics or molecular biology, or permission of the department.

Explores ways in which microbial pathogens, particularly bacteria, interact with their hosts from a molecular and genetics perspective. Topics include general virulence mechanisms of pathogens; bacterial virulence factors and their genetic regulation; molecular genetic approaches to studying pathogenesis; and various model systems which have been used to understand pathogenic mechanisms.

MICR 827.3
Advanced Cellular and Molecular Immunology
2(3-4S)
Prerequisite(s): Permission of the department.

Assesses the current understanding of the immune system, and the experimental means by which this has been achieved, by analyzing papers from the current and past literature.

MICR 850.3
Tumor Biology
2(3S)
Prerequisite(s): BIOC 430 or 830 or permission of the department.

Discussion of current aspects of tumor biology including tumor metastasis, signal transduction, oncogenes and tumor suppressor genes, tumor immunology and tumor markers. Papers from the current scientific literature in these areas will be analyzed.

MICR 898.3
Special Topics
1/2(2L/R)
Prerequisite(s): An introductory Microbiology course and permission of the department.

Study in selected areas of microbiology may be undertaken by senior students with permission of the department. The study will be arranged to suit the requirements of individual students. It may consist of lectures, essays, literature surveys and reports on assigned topics related to a specific subject. Laboratory work may be required.

MICR 990
Seminar

Graduate students are required to present one seminar per year on their research during Term 1 or Term 2 in the Microbiology Graduate Seminar Series. The presentation will include a review of current literature and description of research progress by the student. Yearly registration, attendance and participation is required throughout the graduate program.

MICR 994
Research

Students writing a Master's thesis must register for this course.

MICR 996
Research

Students writing a Ph.D. thesis must register for this course.

  Results 1 - 34 of 34 Courses