Publications

Al-Hendy A, Moshynska O, Saxena A and Feyles V. (2000) Two novel mutations of the gene encoding the follicle stimulating hormone receptor are associated with repeated spontaneous twinning. The Lancet, 356:914.
Baptiste KE, Naylor JM, Bailey J, Barber EM, Post K and Thornhill JA. (2000) A function for guttural pouches in the horse. Nature, 403:382-383.
Bobyn PJ, Franklin JL, Wall CM, Juurlink BHJ, Thornhill JA, and Paterson PG. (2002) Dietary sulphur amino acid deficiency decreases brain glutathione and acerbates neuro damage in a rat model of global hemispheric hypoxic-ischemia. Nutritional Neuroscience, 5, 6:407-416.
Bugiak, B. and Weber, L.P. Hepatic and vascular mRNA expression in adult zebrafish (Danio rerio) following exposure to benzo(a)pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin. Aquatic Toxicology In Press.
B. Daniels, R. J. Linhardt, F. Zhang, W. Mao, S.M. Wice, L. M. Hiebert, 2006. In vivo antithrombotic synergy of oral heparin and arginine: Endothelial thromboresistance without changes in coagulation parameters. Thrombosis and Haemostasis, 95, 865 -872.
Driedger, K., Dubé, M.G., Weber, L.P., Rickwood, C.J. and Janz, D.M. (2009) Testing winter stress syndrome hypothesis. Environmental Toxicology & Chemistry. 28, 296-304.
El-Ghar S, Qureshi M, Shoker A, Prasad K. (2006) “Oxidative Stress in Renal Transplant Patients who Develop Cardiovascular Disease” Journal of Cardiovascular Pharmacology and Therapeutic 11(3): 203-210.
Ghosh M, Wang HD, McNeill JR. (2004) Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA-salt hypertensive rats. Br J Pharmacol, 141(4):562-573.
Goertzen, M. and Weber, L.P. Mechanisms of relaxation in dorsal and ventral aorta in normal and benzo[a]pyrene-exposed trout. Submitted to Comparative Biochemistry and Physiology, Part C – Pharmacology & Toxicology.
L. M. Hiebert, T. Ping, and S. M. Wice, 2008, Enhanced antithrombotic effects of unfractionated heparin in rats after repeated oral doses and its relationship to endothelial heparin concentration. British Journal of Pharmacology, 153, 1177-1184.
Hiebert LM, Wice SM, Ping T, Hileman RE, Capila I & Linhardt RJ. (2000) Tissue distribution and antithrombotic activity of unlabeled or 14c-labeled porcine intestinal mucosal heparin following administration to rats by the oral route. Can J Phvsiol Pharmacol, 78:307-320.
Hopfner RL, Hasnadka RV, McNeill J R, Wilson TW & Gopalakrishnan V. (1998) Insulin increases endothelin-I-evoked [Ca2+]i responses by increased ETA expression in rat aortic smooth muscle cells. Diabetes, 47:937-944.
Jia X, Olson D, Ross A, Wu L. Structural and functional changes in human insulin induced by methylglyoxal. FASEB J. 20(9):1555-1557, 2006.
S.M. Kerfoot, C. Bonder, G. Andonegui and L. Liu. Exogenous stromal cell-derived factor-1 induces subtle leukocyte recruitment in vivo. Am. J. Physiol. Heart Circ. Physiol. 2008; 294(6):H2524-H2534.
Krol ES, Kramer-Stickland K and Liebler DC.(2000) Photoprotective Actions of Topically Applied Vitamin E. Drug Metabolism Reviews, 32 (3&4):413-420.
Krol ES, Escalante DDJ and LieblerDC. (2001) Mechanisms of Dimer and Trimer Formation from Ultraviolet-Irradiated alpha-Tocopherol. Lipids, 36(1):49-55.
Lee P and Prasad K. (2003) Effect of flaxseed oil on serum lipids and atherosclerosis in hypercholesterolemic rabbits. J Cardiovas Pharmacol Therap, 8(3):227-35.
L. Liu, D.C. Cara, J. Jaur, E. Raharjo, S.C. Mullaly, J. Jongstra-Bilen, J. Jongstra, and P. Kubes. LSP1 is an endothelial gate keeper of leukocyte transendothelial migration. J. Exp. Med. 2005; 201(3): 409-418.
L. Liu, K.D. Puri, J.M. Penninger, and P. Kubes. Leukocyte PI3Kg and PI3Kd have temporally distinct roles for leukocyte recruitment in vivo. Blood 2007; 110(4): 1191-1198.
Liu P, Misurski D & Gopalakrishnan V. (2003) Cysteinyl leukotrienes dependent [Ca2+]i responses to angiotensin II in cardiomyocytes. Am J Physiol,284:HI269-H1276.
Liu Y, Zhang W, Chan T, Saxena A and Xiang J. (2002) Enhanced anti-tumor immune responses from fusion of dendritic cells with myeloma cells engineered to secrete IL-4. Leukemia Res, 26:757-763.
Luo J, Zhu T, Evagelidis A, Pato MD and Hanrahan JW. (2000) Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole. Am J Physiol, 279:C108-C119.
Luo J, Pato MD, Riordan JR and Hanrahan JH.(1998) Differential Regulation of single CFTR Channels by PP2C and PP2A and other phosphatases. Am J Physiol, 274:C1397-C1410.
MacDonald MB, Wilson M, Laing G, and Wilson TW. (2003) White coat hypertension in treated hypertensives: a three year follow up study. Can J Cardiovas Nursing, 13:24-29.
McNair, E, Wells C, Qureshi M, Prasad, K. (2006) “Homocysteine and Malondialdehyde as predictors of Restenosis following Percutaneous coronary intervention.” International Journal of Angiology, 15: 69-75
B. Moazed, L. M. Hiebert, 2007. An invitro study with an Ussing chamber showing that unfractionated heparin crosses rat gastric mucosa. The Journal of Pharmacology and Experimental Therapeutics, 322: 299-305.
Ndisang JF, Wu L, Zhao W & Wang R. (2003) Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats. Blood, 101(10):3893-3900.
Pasha M, Selvakumar P, Ashakumary L, Qureshi M, Dimmock JR, Felsted R, Glover CJ and Sharma RK (2004). “Lipidic inhibitors of human N-Myristoyltransferase”. International Journal of Molecular Medicine 13(4): 557-563
Park L and Thornhill J. (2001) Phosphoramidon-sensitive endothelin-converting enzymes modulate cerebral blood flow and neural damage of hypoxic rats. Neuroscience Letters, 301:95-98.
Prasad K and Lee P. (2003) Suppression of oxidative stress as a mechanism of reduction of hypercholesterolemic atherosclerosis by aspirin. J Cardiovas Pharmacol Therap, 8:61-69.
Prasad K, Mantha SV, Kalra J, Lee P. (1997) Prevention of hypercholesterolemic atherosclerosis by garlic, an antioxidant. J Cardiovas Pharmacol Therap, 2:309-319.
Prasad K and Lee P. (2002) Role of oxyradicals in the pathophysiology of hemorrhagic shock. IntI J Angiol, 11:113-128.
Prasad K and Gupta JB. (2002) Relaxant effect of oxygen free radicals on rabbit tracheal smooth muscle. Pulmonary Pharmacol Therapeut, 15:375-3834.
Qureshi M, Khandwala H, Ul-Haq I and Prasad K (2003). “Elevated levels of plasma homocystine in hypertensive patients with Diabetes Mellitus”. Journal of Cardiovascular Pharmacology and Therapeutics 8(4): 261-266
Qureshi M, Zhang X., Ul-Haq I, Xiang, J and Prasad K (2003). “Serum levels of homocystine in mice with malignant tumor”. Experiments in Clinical Cardiology 8(3): 147-149
Ram J & Hiebert LM. (2003) Dextran sulphate protects porcine but not bovine cultured endothelial cells from free radical injury. Can J Vet Res, 67:81-87.
Saxena A, McMeekin JD and Thomas DJ. (2002) Expression of Bcl-x, Bcl-2, Bax and Bak in endarterectomy and atherectomy specimens. J Pathol, 196:335-342.
Shastri SS, McNeill JR, Wilson TW, Poduri R, Kaul CL & Gopalakrishnan V. (2001) Cysteinyl leukotrienes mediate enahnced vasoconstrictor responses to angiotensin II but not endothelin-l in SHR. Am J Physiol, 281: H342-H349 .
Shuaib A., Yang Y, Siddiqui MM, Kalra J. (1998) Intraarterial Urokinase Produces Significant Attenuation of Infarction Volume in an Embolic Focal Ischemia Model. Exptl Neurol, 154:330-335.
Sun D, Wollin A and Stephen A. (2002) Effect of folate deficiency on polyamine synthesis in rats. J Nutr, 132:2632-2637.
Thomas P, Tracy PB, Ping T, Wickstrom M, Sidhu N & Hiebert L. (2003) Relative biological effectiveness (RBE) of 210Po alpha-particles vs. x-rays on lethality in bovine endothelial cells. Internatl J Radiation Biol, 79(2):107-118.
Thornhill J and Corbett D. (2001) Therapeutic implications of hypothermic and hyperthermic temperature conditions in stroke patients. Can J Physiol Pharmacol, 79:254-261.
Wang R. (2002) Two's company, three's a crowd - Can H2S be the third endogenous gaseous transmitter? FASEB J, 16:1792-1798.
Wang R, Wang Z., Wu L, Hanna S.T. & Peterson-Wakeman R. (2001) Reduced vasorelaxant effect of carbon monoxide in diabetes and the underlying mechanisms. Diabetes, 50:166174.
Wang X, Jia X, Chang T, Desai, K, Wu L: Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. J. Hypertens, 26:765-772, 2008.
Weber, L.P. (2004) Acute ex vivo effects of dimethylbenz[a]anthracene and heat shock on rat tail artery. Cardiovascular Toxicology. 4, 355-362.
Weber, L.P., Dubé, M.G., Rickwood, C.J., Driedger, K., Portt, C., Brereton, C. and Janz, D.M. (2008) Assessment of multiple mining and municipal effluents in two fish species collected from Junction Creek, Sudbury, Ontario. Ecotoxicology & Environmental Safety 70, 433-445.
Wilson TR, Wilson M and Wilson TW. (2002) Mineralocorticoid hypertension: common and treatable. Persp. in Cardiol., 18:33-40.
Wollin A, Wang X and Tso P. (1998) Nutrients regulate diamine oxidase release from intestinal mucosa. Am J Physiol, 275: R969-R975.
Wu L, Cao K, Lu Y & Wang R. (2002) Different mechanisms underlying the stimulation of Kca channels by nitric oxide and carbon monoxide. J Clin Inv, 110:691-700.
Wu L, Noyan Ashraf MH, Wang R, Paterson PG, Ferrie A, Juurlink BHJ. (2004) Dietary phase 2 enzyme inducer and its cardiovascular protective effect in stroke prone SHR. Proc Natl Acad Sci USA, 101(18):7094-9.
Wu L, Yang W, Jia X, Yang G, Duridanova D, Cao K, Wang R. Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats. Lab Invest 89(1):59-67, 2009.
Yang G, Wu L, Yang W, Qi J, Jiang B, Cao K, Meng Q, Mustafa AK, Mu W, Snyder SH, Wang R. H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 322:587-590,2008. Co-corresponding author.
Yang G, Yang W, Wu L, Wang R. H2S, endoplasmic reticulum stress, and apoptosis of Insulin-secreting Beta Cells., Apr 12; [Epub ahead of print] PMID: 17430888. J. Biol. Chem 1;282(22):16567-76, 2007.
Yu M, Ghosh M, and McNeill JR. (2003) A novel vasopressin peptide lowers blood pressure through decreases in cardiac output. Can J Physiol Pharmacol, 81: 497-501, RAPID COMMUNICATION.
Yu M, Gopalakrishnan V, Wilson TW, and McNeill JR. (2001) Endothelin antagonist reduces hemodynamic responses to vasopressin in DOCA-salt hypertension. Am J Physiol, 281:H2511-H2517.
Zarnke KB, McAlister FA, Campbell NRC, Levine M, Schiffrin EL, Grover S, McKay DW, Myers MG, Wilson TW, Rabkin SW, Feldman RD, Burgess E, Bolli P, Honos G, Lebel M, Mann K, Abbott C, Tobe S, Petrella R and Touyz R, for the Canadian Hypertension Recommendations Group. (2002) The 2001 Canadian recommendations for the management of hypertension: Part one-Assessment for diagnosis, cardiovascular risk, causes and lifestyle modification. Can J Cardiol, 18:604-624.
Zarnke KB, Levine M, McAlister FA, Campbell NRC, Myers MG, McKay DW, Bolli P, Honos G, Lebel M, Mann K, Wilson TW, Abbott C, Tobe S, Burgess E and Rabkin S., for the Canadian Hypertension Society Working Group (2001) The 2000 Canadian recommendations for the management of hypertension: Part two - diagnosis and assessment of people with high blood pressure, Can J Cardiol, 17:1249-1263.
