Publications
Peer reviewed and scientific correspondence for the last 10 years
173. Pickering, I.J., Gumaelius, L., Harris, H.H., Prince, R.C., Hirsch, G., Banks, J.A., Salt, D.E., George, G.N. (2006). “Localizing the biochemical transformations of arsenate in a hyperaccumulating fern”. ES&T. (in press).
172. Hoffmeyer R., Singh, S.P., Doonan, C.J., Ross, A.R.S., Hughes, R.J., Pickering, I.J., George, G.N. (2006). “Molecular mimicry in mercury toxicology”. Chem. Res. Toxicol. 19, 753-759.
171. Manley, S.A.; George, G.N.; Pickering, I.J.; Glass, R.S.; Prenner, E.J.; Yamdagni, R.; Wu, Q,; Gailer, J. (2006) “The Seleno Bis(S-glutathionyl) Arsinium Ion Is Assembled in Erythrocyte Lysate”. Chem. Res. Toxicol. 19, 601-607.
170. Harris, H.H., George, G.N., Rajagopalan, K.V. “High resolution EXAFS of the active site of sulfite oxidase: Comparison with density functional and x-ray crystallographic results”. (2006). Inorg. Chem. 45, 493-495.
169. Doonan, C.J., Nielsen, D.J., Smith, P.D., White, J.M., George, G.N.; Young, C.G. (2006). “Models for the molybdenum hydroxylases: Synthesis, characterization and reactivity of cis-oxosulfido-Mo(VI) complexes”. J. Am. Chem. Soc. 128, 305-316.
168. Horng, Y-C, Leary, S.C., Cobine, P.A., Young, F.B.J., George, G.N., Shoubridge, E.A., Winge D.R. (2005). “Human Sco1 and Sco2 function as copper-binding proteins”. J. Biol. Chem. 280, 34113-34122.
167. George, G.N. (2005). “Pondering potash”. Chem. & Eng. News, 83, 3-4.
166. Akabayov, B., Doonan, C.J., Pickering, I.J., George, G.N., Sagi, I. (2005). “ Using softer x-ray absorption spectroscopy to probe biological systems”. J. Synch. Rad. 12, 392-401.
165. Lane, T., Saito, M.A., George, G.N., Pickering, I.J., Prince, R.C., Morel, F.F.M. (2005). “A cadmium enzyme from a marine diatom”. Nature, 435, 42.
164. Doonan, C.D., Zhang, L., Young, C.G., George, S.J., Bergmann, U., George, G.N., Cramer, S.P. (2005). “High resolution x-ray emission spectroscopy of molybdenum complexes”. Inorg. Chem. 44, 2579-2581.
163. Doonan, C.J., Stockert, A., Hille, R., George G.N. (2005). “Nature of the catalytically labile oxygen at the active site of xanthine oxidase”. J. Am. Chem. Soc. 127, 4518-4522.
162. George, G.N., Garret, R.M., Prince, R.C., Rajagopalan, K.V. (2004). “ Coordination chemistry at the molybdenum site of sulfite oxidase: Redox-induced structural changes in the cysteine 207 to serine mutant”. Inorg. Chem. 43, 8456-8460.
161. George, G.N., Prince, R.C., Gailer, J. Buttigieg, G.A., Denton, M.B., Harris, H.H. and Pickering, I.J. (2004). “Mercury binding to the chelation therapy agents DMSA and DMPS, and the rational design of custom chelators for mercury”. Chem. Res. Toxicol. 17, 999-1006.
160. Vickerman, D.B., Trumble, J.T., George, G.N., Pickering, I.J., Nichol, H. (2004). “Selenium biotransformation in an insect ecosystem: Effects of insects on phytoremediation”. Environ. Sci. Technol. 38, 3581-3586.
159. Xiao, Z., Loughlin, F., George, G.N., Howlett G.J., Wedd, A.G. (2004). “The C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu(I) ions as a cuprous-thiolate polynuclear cluster. Sub-femtomolar Cu(I) affinity of three proteins involved in copper trafficking”. J. Am. Chem. Soc. 126, 3081-3090.
158. Harris, H.H., Pickering, I.J., George, G.N. (2004). “More on mercury content in fish”. Science, 303, 764-776 (correspondence).
157. George, G N. (2004) “Not So Hot”. Chem. & Eng. News. 82, 8.
156. Maher, M.J. Santini, J. Pickering, I.J., Prince, R.C., Macy, J.M., George, G.N. (2004). “X-ray Absorption Spectroscopy of Selenate Reductase”. Inorg. Chem. 43, 402-404.
155. Sneeden, E.Y., Harris, H.H., Pickering, I.J., Prince, R.C., Johnson, S., Li, X., Block, E., George, G.N. (2004). “The Sulfur Chemistry of Shiitake Mushroom”. J. Am. Chem. Soc. 126, 458-459.
154. Kim, Y-B, Garbisu, C., Pickering, I.J., Prince, R.C., George, G.N., Cho, M-J, Wong, J.H., Buchanan, B.B. (2003). “Thioredoxin h overexpressed in barley seeds enhances selenite resistance and uptake during germination and early seedling development”. Planta, 218, 186-191.
153. Thomas, S., Eagle, A.A., Hill, J.P., Sproules, S.A., White, J.M., Tiekink, E.R.T., George, G.N., Young, C.G. (2003). “Redox Interplay of Oxo-thio-tungsten Centers with Sulfur-donor co-ligands”. Inorg. Chem. 42, 5909-5916.
152. Harris, H.H., Pickering, I J., George, G.N. (2003). “The chemical form of mercury in fish”. Science, 381, 1203.
151. Leimkühler, S., Hodson, R., George, G.N., Rajagopalan, K.V. (2003). “Heterologous expression of Rhodobacter capsulatus xanthine dehydrogenase in Escherichia coli and characterization of the recombinant enzyme”. J. Biol. Chem. 278, 20802-20811.
150. Nichol, H., Gakh, O., Pickering I.J., Grazia, I., George, G.N. (2003). “The structure of yeast frataxin iron cores: An X-ray absorption spectroscopic study”. Biochemistry 42(20), 5971-5976.
149. Pickering, I.J., Hirsch, G., Prince, R.C., Sneeden, E.Y., Salt, D.E., George, G.N. (2003). “Imaging of selenium in plants using tapered metal monocapillary optics”. J. Sync. Rad. 10, 289-290.
148. Pickering, I.J., Wright, C., Bubner, B., Persans, M.W., Yu, E.Y., George, G.N., Prince, R.C., Salt, D.E. (2003). “Chemical form and distribution of selenium and sulfur in the selenium hyperaccumulator Astragalus bisulcatus”. Plant Physiol. 131, 1460-1467.
147. George, G.N., Pickering, I.J., Harris, H.H., Gailer, J., Klein, D., Lichtmannegger, J., Summer, K-H. (2003). “Tetrathiomolybdate causes formation of hepatic copper-molybdenum clusters in an animal model of Wilson’s disease”. J. Am. Chem. Soc. 125, 1704-1705.
146. Gailer, J., George, G.N., Pickering, I.J. Prince R.C., Younis, H.S., Winzerling, J.J. (2002). “Biliary excretion of [(GS)2AsSe]- after intravenous injection of rabbits with arsenite and selenate”. Chem. Res. Toxicol. 15, 1466-1471.
145. Hale, K.L., Tufan, H.A., Pickering, I.J., George, G.N., Terry, N., Pilon, M., Pilon-Smits, E.A.H. (2002). “Anthocyanins facilitate tungsten accumulation in Brassica”. Physiologia Plantarum. 116, 351-358.
144. Gailer, J., George, G.N., Harris, H.H., Pickering, I.J., Prince, R.C., Buttigieg, G.A., Glass, R.S., Denton, M.B. (2002). “Synthesis, purification and structural characterization of the dimethyldiselenoarsinate anion”. Inorg. Chem. 41, 5427-5432.
143. Conrads, T., Hemann, C., George, G.N., Pickering, I.J., Prince, R.C., Hille, R. (2002). “The Active Site of Arsenite Oxidase from Alcaligenes faecalis.” J. Am. Chem. Soc. 124, 11276-11277.
142. Cross, M., Xiao, Z., Maes, E.M., Czernuszewicz, R.S., Drew, S.C., Pilbrow, J.R., George, G.N., Wedd, A.G. (2002). “Removal of a cysteine ligand from rubredoxin: assembly of Fe2S2 and Fe(S-Cys)3(OH) centers”. J. Biol. Inorg. Chem. 7, 781-790.
141. George, G.N., Pickering, I. J., Yu, E. Y., Prince, R. C. (2002) “X-ray absorption spectroscopy of bacterial sulfur globules”. Microbiology, 148, 2267-2268.
140. Carr, H.S., George G. N., Winge D. R. (2002). “Yeast Cox11, a protein essential for cytochrome c oxidase assembly, is a Cu(I)-binding protein”. J. Biol. Chem. 277(34), 31237-31242.
139. Brown, K.R., Keller, G., Pickering, I.J., George, G.N., Winge, D.R. (2002). “The Structures of the Cuprous Thiolate Clusters of the Ace1 and Mac1 Transcriptional Activators”. Biochemistry 41, 6469-6467.
138. Cobine, P.A., George, G.N., Jones, C.E., Wickramasinghe, W.A., Solioz, M., Dameron, C.T. (2002). “Copper Transfer from the Cu(I) Chaparone, CopZ, to the Repressor, Zn(II)CopY: Metal Coordination Environments and Protein Interactions”. Biochemistry, 41, 5822-5829.
137. Gailer, J., George, G.N., Pickering, I.J., Buttigieg, G.A., Denton, M.B., Glass, R.S. (2002). “Synthesis, X-ray Absorption and purification of the seleno-bis (S-glutathionyl) arsinium anion from selenide, arsenite and glutathione”. J. Org. Met. Chem. 650, 108-113.
136. Ferreira, G.C., Franco, R., Mangravita, A., George, G.N. (2002). “Unravelling the Substrate-Metal Binding Site of Ferrochelatase: An X-ray Absorption Spectroscopic Study”. Biochemistry 41, 4809-4818.
135. Hill, L. M.R., George, G.N., Duhme-Klair, A-K, Young, C.G. (2002). “Solution structural studies of molybdate-nucleotide polyanions”. J. Inorg. Biochem. 89, 278-283.
134. Clay, M.D., Jenney, F.E., Hagedoorn, P.L., George, G.N., Adams, M.W.W., Johnson, M.K. (2002). “Spectroscopic Studies of Pyrococcus furiosus Superoxide Reductase: Implications for Active Site Structure and the Catalytic Mechanism”. J. Am. Chem. Soc. 124, 788-805.
133. Nittis, T., George, G.N., Winge, D.R. (2001). “Yeast Sco1, a Protein Essential for Cytochrome c Oxidase Function Is a Cu(I)-binding Protein”. J. Biol. Chem. 276, 42520-42526.
132. Gailer, J., George, G.N., Pickering, I.J., Prince, R.C., Kohlhepp, P., Zhang, D., Walker, F.A., Winzerling, J.J. (2001). “Human Cytosolic Iron Regulatory Protein 1 Contains a Linear Iron-Sulfur Cluster”. J. Am. Chem. Soc. 123, 10121-10122.
131. Hu, Z., George G.N. and Gorun, S.M. (2001). “Fluorine Encapsulation and Stabilization of Biologically Relevant Low-Valence Copper-Oxo Cores”. Inorg. Chem. 40, 4812-4813.
130. Yu, E.Y., Pickering, I.J., George, G.N., Prince, R.C. (2001). “In-situ observation of the generation of isothiocyanates from sinigrin in horseradish and wasabi”. Biochim. Biophys. Acta 1527, 156-160.
129. Pickering, I.J., George, G.N., Yu, E.Y., Brune, D.C., Tuschak, C., Overmann, J., Beatty, J.T., Prince, R C. (2001). “Analysis of Sulfur Biochemistry of Sulfur Bacteria Using X-ray Absorption Spectroscopy”. Biochemistry 40, 8138-8145.
128. Hale, K.J., McGrath, S., Lombi, E., Stack, S., Terry, N., Pickering, I.J., George, G.N., Pilon-Smits, E.A.H. (2001). “Molybdenum sequestration in Brassica: A role for anthocyanins?” Plant Physiology 126, 1391-1402.
127. Young, C.G., Gable, R.W., Hill, J.P., George, G.N. (2001). “Mononuclear Thiomolybdenyl Complexes: Synthesis, Structural and Spectroscopic Characterization”. Eur. J. Inorg. Chem. 9, 2227-2231.
126. Eagle, A.A., Tiekink, E.R.T., George, G.N., Young, C.G. (2001). “Synthesis, Characterization and Electrochemistry of cis-Oxo-thio- and cis-Bis(thio)-tungsten(VI) Complexes of Hydrotris(3,5-dimethylpyrazol-1-ly)borate”. Inorg. Chem. 40, 4563-4573.
125. Grossman, M.J., Lee, M.K., Prince, R.C., Minak-Bernero, V., George G.N., Pickering, I.J. (2001). “Deep Desulfurization of Extensively Hydrodesulfurized Middle Distillate Oil by Rhodococcus sp. Strain ECRD-1”. Applied and Environmental Microbiology 67, 1949-1952.
124. Heaton, D.N., George, G.N., Garrison, G., Winge, D.R. (2001). “The Mitochondrial Copper Metallochaperone Cox17 exists as a Oligomeric”. Polycopper Complex. Biochemistry 40, 743-751.
123. Gailer, J. George, G.N., Pickering, I.J., Madden, S, Prince, R.C., Yu, E.Y., Denton, M.B., Younis H.S. and Aposhian, H.V. (2000). “The Structural Basis of the Antagonism between Inorganic Mercury and Selenium in Mammals”. Chem. Res. Toxicol. 13, 1135-1142.
122. Polette, L.A., Gardea-Torresdey, J L., Chianelli, R.R., George, G.N., Pickering I.J., Arenas, J. (2000). “XAS and microscopy studies of the uptake and bio-transformation of copper in Larrea tridentata (creosote bush)”. Microchem. J. 65, 227-236.
121. Van Fleet-Stalder, V., Chasteen, T.G., Pickering, I.J., George, G.N., Prince, R.C. (2000). “The fate of selenate and selenite metabolized by Rhodobacter sphaeroides”. Applied and Environmental Microbiology 66, 4849-4853.
120. Cox, E.H., McLendon, G.L., Morel, F.M.M Prince, R.C., Pickering, I.J., George G.N. (2000). “The active site structure of Thalassiosira weissflogii Carbonic Anhydrase 1”. Biochemistry 39, 12128-12130.
119. Pickering, I.J., Prince, R.C., Salt, D.E., George, G.N. (2000). “Quantitative chemically-specific imaging of selenium transformation in plants”. Proc. Natl. Acad. Sci. U.S.A. 97, 10717-10722.
118. George, G.N., Pickering, I.J., Yu, E.Y., Prince, R.C., Bursakov, S.A., Gavel, O.Y., Moura, I. and Moura J.J.G. (2000). “A Novel Protein-Bound Copper-Molybdenum Cluster”. J. Am. Chem. Soc. 132, 8321-8322.
117. Combine, P.A., George, G.N., Winzor, D.J., Harrison, M.D., Mogahaddas, S., Dameron, C.T. (2000). “Stoichiometry of Complex Formation between Copper(I) and the N-Terminal Domain of the Menkes Protein”. Biochemistry 39, 6857-6863.
116. Gailer, J., George, G.N., Pickering, I.J., Prince, R.C., Ringwald, S.C., Pemberton, J. C., Glass, R.S., Younis, H.S., DeYoung, D.W., Aposian, H.V. (2000). “A Metabolic Link Between As(III) and Se(IV): The Seleno-bis(S-glutathionyl)Arsinium Ion”. J. Am. Chem. Soc., 122, 4637-4639.
115. Temple C.A, George G.N., Hilton, J.C., George, M.J., Prince, R.C, Barber, M.J., and Rajagopalan, K.V. (2000). “Structure of the Molybdenum Site of Rhodobacter sphaeroides Biotin Sulfoxide Reductase”. Biochemistry 39, 4046-4052.
114. Smith, P.D., Slizys, D.A, George, G.N. and Young C.G. (2000). “Towards a total model for the molybdenum hydroxylases: Synthesis, redox and biomimetic chemistry of oxo-thio-Mo(VI) and -Mo(V) complexes”. J. Am. Chem. Soc. 122, 2946-2947.
113. Pickering, I.J., Prince, R.C., George, M.J., Smith, R.D. George G.N. and Salt, D.E. (2000). “Reduction and Coordination of Arsenic in Indian Mustard”. Plant Physiol. 122, 1171-1177.
112. Pickering, I.J., George, G.N., van Fleet-Stalder, V., Chasteen, T.G., Prince, R.C. (1999). “X-ray absorption spectroscopy of selenium-containing amino acids”. J. Biol. Inorg. Chem. 4, 791-794.
111. George, G.N., Mertens, J.A., Campbell, W.A. (1999). “Structural Changes Induced by Catalytic Turnover at the Molybdenum Site of Arabidopsis Nitrate Reductase”. J. Am. Chem. Soc. 121, 9730-9731.
110. Eagle, A.A., George, G.N., Tiekink, E.R.T., Young, C.G. (1999). “Generation and biomimetic chemistry of tungsten-dithiolene complexes containing the hydrotris (3,5-dimethlypyrazole-1-yl) borate ligand”. J. Inorg. Biochem. 76, 39-45.
109. George, G.N., Pickering, I.J., Kisker, C. (1999). “X-ray Absorption Spectroscopy of Chicken Sulfite Oxidase Crystals”. Inorg. Chem. 38, 2539-2540.
108. George, G.N., Costa, C., Moura, J.J. G., Moura, I. (1999). “Observation of Ligand-Based Redox Chemistry at the Active Site of a Molybdenum Enzyme”. J. Am. Chem. Soc. 121, 2625-2626.
107. George, G.N., Hilton, J. Temple, C., Prince, R.C., Rajagopalan, K.V. (1999). “The Structure of the Molybdenum Site of Dimethylsulfoxide Reductase”. J. Am. Chem. Soc. .121, 1256-1266.
106. Pickering, I.J.; Prince, R.C.; George, G.N., Rauser, W.E., Wickramasinge, W A., Watson, A.A., Dameron, C.T., Dance, I.G., Fairlie, D.P., Salt, D.E. (1999). “X-ray Absorption of Cadmium Phytochelatin and Model Systems”. Biochim. Biophys Acta. 1429, 351-364.
105. Grossman, M.J., Lee, M.K., Prince, R.C., Garrett, R.M., George, G.N. and Pickering, I.J. (1999). “Microbial desulfurization of a crude oil middle-distillate fraction; analysis of the extent of sulfur removal and the effect of removal on remaining sulfur”. Appl. Environ. Microbiol. 65, 181-188.
104. Pickering, I.J., Prince, R.C., Divers, T.C. and George, G.N. (1998). “Sulfur K-edge X-ray Absorption Spectroscopy for Determining the Chemical Speciation of Sulfur in Biological Systems”. FEBS Letters 441, 11-14.
103. Gavel, O.Y., Bursakov, S.A., Calvete, J.J., George, G.N., Moura, J.J.G., Moura, I. (1998). “ATP sulfurylases from sulfate-reducing bacteria of the genus Desulfovibrio. A novel metalloprotein containing cobalt and zinc”. Biochemistry 37, 16225-16232.
102. George, G.N., Hedman, B., Hodgson, K.O. (1998). “An edge with XAS”. Nature Structural Biology 5, 645-647.
101. Srinivasan, C., Posewitz, M.C., George, G.N., Winge, D.R. (1998). “Characterization of the Copper Chaperone Cox17 of Saccharomyces cerevisiae”. Biochemistry 37, 7572-7577.
100. George, G.N., Garrett, R.M., Graf, T., Prince, R.C. and Rajagopalan, K.V. (1998). “On the Interaction of Arsenate with the Molybdenum Site of Sulfite Oxidase”. J. Am. Chem. Soc. 120, 4522-4523.
99. Xiao, Z., Lavery, M.J., Ayhan, M., Scrofani, S.D.B., Wilce, M.C.J., Guss, J.M.G., Tregloan, P.A., George, G.N. and Wedd, A.G. (1998). “The Rubredoxin from Clostridium pasteurianum: Mutation of the Iron Cysteinyl Ligands to Serine. Crystal and Molecular Structures of Oxidized and Dithionite-treated Forms of the Cys42Ser Mutant”. J. Am. Chem. Soc. 120, 4135-4150.
98. George, G.N., Colangelo, C.M., Dong, J., Scott, R.A., Khangulov, S.V., Gladyshev and V.N. Stadtman, T.C. (1998). “X-ray Absorption Spectroscopy of the Molybdenum site of Escherichia coli Formate Dehydrogenase”. J. Am. Chem. Soc. 120, 1267-1273.
97. George, G.N. (1997). “X-ray Absorption Spectroscopy of Molybdenum enzymes”. J. Biol. Inorg. Chem. 2, 790-796.
96. Eagle, A.A., George, G.N., Tiekink, E.R.T., Young, C.G. (1997). “ Oxotungsten(VI) Chemistry of Hydrotris(3,5-dimethylpyrazol-1-yl)borate: (Hydroxo)dioxotungsten(VI), Trioxotungsten(VI) and (m-oxo)bis[dioxotungsten(VI)] Complexes”. Inorganic Chemistry 36, 472-479.
95. Prince, R.C., George, G.N. (1997). “The Remarkable Complexity of Hydroxylamine Oxidoreductase”. Nature Structural Biology 4, 245.
94. Graden, J.A., Posewitz, M.C., Simon, J.R., George, G.N., Pickering, I.J., Winge, D.R. (1996). “Presence of a Cu(I)-Thiolate Regulatory Domain in the Copper-Activated Transcription Factor Amt1”. Biochemistry 35, 14583-14589.
93. Laplaza, C.E., Johnson, M.A., Peters, J., Odom, A.L., Kim, E., Cummins, C.C., George, G.N., Pickering, I.J. (1996). “Dinitrogen Cleavage by Three-Coordinate Molybdenum (III) Complexes: Mechanistic and Structural Data”. J. Am. Chem. Soc. 118, 8623-8638.
92. George, G.N., Garrett, R.M., Prince, R.C., Rajagopalan, K.V. (1996). “The Molybdenum Site of Sulfite Oxidase: A Comparison of Wild-type and the Cysteine 207 to Serine Mutant using X-ray Absorption Spectroscopy”. J. Am. Chem. Soc. 118, 8588-8592.
91. George, G.N., Pickering, I.J., Prince, R.C., Zhou, Z-H., Adams, M.W.W (1996). “X-ray Absorption Spectroscopy of Pyrococcus furiosus Rubredoxin”. J. Biol. Inorg. Chem. 1, 226-230.
90. George, G.N., Hilton, J., Rajagopalan, K.V. (1996). “X-ray Absorption Spectroscopy of Dimethylsulfoxide Reductase from Rhodobacter sphaeroides”. J. Am. Chem. Soc. 118, 1113-1117.
89. George, G.N., Prince, R.C., Bare, R.E. (1996). “ Electron Paramagnetic Resonance spectroscopy of the iron-molybdenum cofactor of Clostridium pasteurianum nitrogenase”. Inorg. Chem. 35, 434-438.