Dr. Jim FangB.Sc.(China Pharmaceutical University); Ph.D.(King's College London)
Associate Professor of Pharmacy
2D30.1 Health Sciences
Dr. Fang joined the faculty in 1999.
- Teaching Responsibilities
Pharmacokinetics and Biopharmaceutics.
- Research Interests
Dr. Fang's laboratory is conducting studies on the pharmacokinetics and health effects of antioxidants in prairie fruits. Recent studies include the factors influencing the absorption of saskatoon berry antioxidants in human volunteers. The laboratory is also perusing studies on the absorpion, distribution, metabolism and excretion of anthocyanins. Current projects include the mechanisms of absorption and presystemic metabolism of anthocynanins. Dr. Fang has published over 30 peer-reviewed scientific articles.
- Recent Publications (see more in Scopus)
Fang J. (2014) Some anthocyanins could be efficiently absorbed across the gastrointestinal mucosa: Extensive presystemic metabolism reduces apparent bioavailability. J Agri Food Chem 62, 3904-3911.
Fang J and Mosier KE. (2014) Literature values of terminal half-lives of clozapine are dependent on the time of the last data point. J Pharm Pharmaceu Sci 17(2): 187-189.
Fang J and Song JX. (2012) In vitro characterization of the oxidation of a pyridinium metabolite of haloperidol by human placenta: The effect of smoking. J. Pharm. Pharmaceu. Sci. 15(4), 538-547.
Luo JP, Vashishtha SC, Hawes EM, McKay G, Midha KK, and Fang J. (2011) In vitro identification of cytochrome P450 isoforms involved in the oxidative metabolism of loxapine. Biopharmaceutics & Drug Disposition 32(7), 398-407.
- Research Category Keywords
Drug Metabolism, Pharmacokinetics, Cytochrome P450, Bioavailability, First-pass effect, Antioxidants, Saskatoon berries