Dr. Jim Fang
B.Sc.(China Pharmaceutical University); Ph.D.(London)
Associate Professor of PharmacyThorvaldson G20
Phone: 306-966-6372
Fax: 306-966-6377
jim.fang@usask.ca
Dr. Fang joined the faculty in 1999.
Teaching Responsibilities:
Undergraduate courses in Pharmacokinetics and Biopharmaceutics.
Research Interests:
Drug metabolism and pharmacokinetics. Recent studies have involved tastes of pharmaceuticals and their relationship with pharmacological effects.
Recent Publications:
J. Fang, H. Semple and J-X. Song, 2004. HPLC Analysis of Metoprolol and Four of its Metabolites, Journal of Chromatography B., 809(1), 9-14.
K.E. Mosier, J-X. Song, G. McKay, J.W. Hubbard and J. Fang, 2003. Determination of clozapine, and its Metabolites, N-desmethyl Clozapine and Clozapine N-oxide Using High Performance Liquid Chromatography in Dog Plasma. Journal of Chromatography B. 783, 377-382.
J. Fang, G. McKay, J.W. Hubbard, E.M. Hawes and K.K. Midha, 2000. Dose Staggering as a Strategy to Reduce Drug-drug Interactions Due to Reversible Enzyme Inhibition between Orally Administered Drugs with High First Pass Effect: A Computer Simulation Study, Biopharmaceutics and Drug Disposition, 21, 249-259.
J. Fang, M. Bourin and G.B. Baker, 1999. Involvement of CYP2D6 and CYP3A4 in the Metabolism of Risperidone to 9-hydroxyrisperidone, Naunyn-Schmiedeberg’s Archives in Pharmacology, 358, 147-151.
J. Fang and J.W. Gorrod, 1999. Metabolism, Pharmacogenetics and Metabolic Drug-Drug Interactions Involving Antipsychotic Drugs (Review), Cellular and Molecular Neurobiology, 19, 491-510.
J. Fang, R.T. Coutts, K.F. McKenna and G.B. Baker, 1998. Elucidation of Individual Cytochrome P450 Isoenzymes Involved in the Metabolism of Clozapine, Naunyn-Schmiedeberg’s Archives in Pharmacology, 358, 592-599.
J.W. Gorrod and J. Fang, 1993. On the Metabolism of Haloperidol, Xenobiotica, 23, 495-508.
Research Category Key Words:
Drug Metabolism, Pharmacokinetics, In Vitro/In Vivo Correlation, Drug Interaction, Cytochrome P450, Computer Modeling, Herbal Medicine.
