Dr. Jim Fang
B.Sc.(China Pharmaceutical University); Ph.D.(London)Associate Professor of Pharmacy
Dr. Fang joined the faculty in 1999.
Undergraduate courses in Pharmacokinetics and Biopharmaceutics.
Drug metabolism and pharmacokinetics. Recent studies have involved tastes of pharmaceuticals and their relationship with pharmacological effects.
J. Fang, H. Semple and J-X. Song, 2004. HPLC Analysis of Metoprolol and Four of its Metabolites, Journal of Chromatography B., 809(1), 9-14.
K.E. Mosier, J-X. Song, G. McKay, J.W. Hubbard and J. Fang, 2003. Determination of clozapine, and its Metabolites, N-desmethyl Clozapine and Clozapine N-oxide Using High Performance Liquid Chromatography in Dog Plasma. Journal of Chromatography B. 783, 377-382.
J. Fang, G. McKay, J.W. Hubbard, E.M. Hawes and K.K. Midha, 2000. Dose Staggering as a Strategy to Reduce Drug-drug Interactions Due to Reversible Enzyme Inhibition between Orally Administered Drugs with High First Pass Effect: A Computer Simulation Study, Biopharmaceutics and Drug Disposition, 21, 249-259.
J. Fang, M. Bourin and G.B. Baker, 1999. Involvement of CYP2D6 and CYP3A4 in the Metabolism of Risperidone to 9-hydroxyrisperidone, Naunyn-Schmiedeberg’s Archives in Pharmacology, 358, 147-151.
J. Fang and J.W. Gorrod, 1999. Metabolism, Pharmacogenetics and Metabolic Drug-Drug Interactions Involving Antipsychotic Drugs (Review), Cellular and Molecular Neurobiology, 19, 491-510.
J. Fang, R.T. Coutts, K.F. McKenna and G.B. Baker, 1998. Elucidation of Individual Cytochrome P450 Isoenzymes Involved in the Metabolism of Clozapine, Naunyn-Schmiedeberg’s Archives in Pharmacology, 358, 592-599.
J.W. Gorrod and J. Fang, 1993. On the Metabolism of Haloperidol, Xenobiotica, 23, 495-508.
Research Category Key Words:
Drug Metabolism, Pharmacokinetics, In Vitro/In Vivo Correlation, Drug Interaction, Cytochrome P450, Computer Modeling, Herbal Medicine.