The principal investigator is the key person responsible for ensuring that all animal use and manipulations are conducted according to the procedures approved in the protocol, and that all guidelines for humane treatment and use are met. The principal investigator is responsible for the conduct of all the people associated with the protocol; graduate students, research technicians, undergraduate students.
UCACS monitoring of the animals while the research is in progress occurs in several ways and is an ongoing part of the animal care and use program.
All proposed use of animals for research, teaching, testing and display must receive ethical review, and be approved by the UCACS, before the animals are obtained and the work initiated. Requests to use animals must be submitted on the appropriate animal use protocol form.
Procedures for Ethics Review of Animal Use Protocols
Ethical review of animal use protocols is performed by the UCACS Animal REB. The Animal REB meets monthly on the fourth Wednesday of the month. Deadline for receipt of new protocols in the Research Ethics Office for review that month is the first Friday of the month.
Annual Review of Ongoing Protocols
Ethics approval of animal-based research protocols is issued for one year at a time, in compliance with the CCAC guidelines and the UCACS Terms of Reference. If the research project continues beyond one year, the principal investigator must submit a completed "Annual Review Report" form to the Research Ethics Office prior to the one-year anniversary approval date. A reminder of the upcoming annual review will be sent to the principal investigator at least two months prior to the anniversary approval date. If the Annual Review Report form is not received by the anniversary approval date, the Research Ethics Office will send a second reminder to the principal investigator indicating that the study will be closed one month after the anniversary date. If the Annual Review Report form is not received within one month of the second reminder, the protocol will be considered "completed".
During the course of the year (prior to the annual review), if any changes
are required (e.g. different species or strain, increase in numbers of animals,
change in animal procedures) these modifications must first be approved by
the AREB, before the changes can be incorporated into the research program.
Modification requests must be submitted on the Animal Use Protocol (AUP) Modification Form. Determination as to whether a protocol modification is required, follows the UCACS Procedures on Submission of a Modification to an Existing Animal Use Protocol.
A formal, structured Post-Approval Review (PAR) of animal use protocols, supplementing the activities already in place at the University is currently under development.
The purposes of the Post-Approval Review Program are:
It is difficult to generalize about provincial/territorial permits. In most provinces/territories, the authority for species other than migratory birds protected by the federal Migratory Birds Convention Act falls under the permitting jurisdiction of the provincial/territorial Natural Resources Department. Having an Environment Canada Scientific Research Permit may not satisfy all permit requirements for research. Contact the appropriate provincial/territorial Department of Natural Resources for more complete information.
Provincial and Federal Permit Links