Key Researchers

Bone Imaging Group

The Saskatchewan Health Research Foundation have announced funding for a Bone and joint Imaging Group (BIG) – a formalized, interdisciplinary Bone Research Group. In addition, a CRC Tier 2 position in Bone and Joint Imaging will be filled in July 2009 to lead this group.

Adam Baxter-Jones (Kinesiology)

Adam is an expert in human growth studies and longitudinal data analysis, and leads the world’s longest-running bone accrual study, now in its 17th year of data collection. The study has identified the links between childhood growth, physical activity, and calcium intake on bone accrual in adolescence and subsequent bone health in the third decade of life.

The Cost of Being an Inactive Kid: In an age where gaming and TV increasingly rule children's time, the research of Baxter-Jones and his University of Saskatchewan colleagues reveals the surprising costs of being a couch-potato kid. Read more »

What prevents adolescent girls from being physically active? The effects and interaction of growth and maturation Read more »

U of S Team Develops New Method to Predict Adult Height in Children Read more »

Saija Kontulainen (Kinesiology)

Saija’s studies have indentified bone structural alterations as they related to mechanical loading in humans. This work has revealed differences in the ways boys and girls develop mechanical bone strength during puberty.

The relationship of physical development and physical activity during childhood and adolescence to bone strength at 50 years of age.

Read more »

Strength indices from pQCT imaging predict up to 85% of variance in bone failure properties at tibial epiphysis and diaphysis Read more »

David Cooper (Medicine)

David is an expert in the emerging use of high-resolution 3D micro-computed tomography to study bone tissue turnover. He has published the first studies to visualize bone porosity non-destructively in 3D.

David’s collaboration with the University of Melbourne is facilitating access to one of the best repositories of modern human bone specimens – the Melbourne Femur Collection. This partnership has initiated high-resolution bone aging studies at synchrotrons in the USA (Advanced Photon Source, Chicago), and Japan (Spring 8).

CFI Awards $661,310 to U of S Research on Hepatitis C, Osteoporosis, Strokes Read more »

A multi-level analysis of differences between normal and osteoporotic bone Read more »

Gene Expression Mapping with Synchrotron Light (GEMS) Group

The GEMS group was founded by Dean Chapman and has nine members including two Tier 1 CRC’s, one Tier 2 CRC, all of which are synchrotron users.

The focus of GEMS is to establish and use X-ray methods to visualize when and where a gene of interest is expressed by cells in whole animals in vivo (in a living organism)

Dean Chapman (CRC Tier 1, Medicine)

Dean is founder of the GEMS research group and team leader of the BMIT beamline at the CLS. His is an internationally-recognised expert in biomedical applications of synchrotron light and a pioneer in the area of Diffraction-Enhanced Imaging (DEI), a specialized method which uses the synchrotron to provide image contract based upon diffraction and scattering, not simply absorption of X-rays.

Dean’s work with the Brookhaven synchrotron in the US, is accelerating research into the biomedical application of DEI.

Dean Chapman shares his enthusiasm for the power of interdisciplinary partnerships which he believes could help make the U of S a world leader in biomedical research. Read more »

Partnership with Biomedical Imaging and Therapy Program Read more »

Graham George (CRC Tier 1, Arts & Science)

World-renowned expert on X-ray Absorption Spectroscopy, Graham has published extensively. His work includes ground-breaking application of XAS to mammalian toxicology, and in collaboration with Ingrid Pickering, has laid the research groundwork for a Phase III clinical trial to combrat wide-spread arsenicosis in rural Bangladesh.

Graham George Home Page

Toxicology Centre

BioXAS: Life science synchrotron beamlines for x-ray absorption spectroscopy for the Canadian Light Source Read more »

Graham George and the Synchrotron

Ingrid Pickering (Tier 2 CRC, Arts & Science)

Ingrid is co-lead of the BioXAS beamline. She is a world-renowned expert on micro X-ray fluorescence imaging and spectroscopy. She pioneered the use of XAS in the fields of environmental health science and in molecular toxicology, and developed new methods for chemically-specific X-ray imaging.

Ingrid and her colleagues recently submitted an application to the CIHR Strategic Training Inititive in Health Research program, which aims to establish a synchrotron health training program that will engage a broach multidisciplinary research community.

More on Ingrid Pickering

Ingrid Pickering and the Synchrotron

CLS Life Science Theme Workshop Read more »

Tissue Engineering Group

This group has nine members, including one Tier 2 CRC and is led by Daniel Chen.