TERM 1 - 2013-2014 

TERM 2 - 2013-2014

New Course being offered Term 1 2013-14

TOX 400.3
Quantative Toxicology

Steven D Siciliano, Mark Wickstrom,  Jane Alcorn
Office: 5E26 Agriculture
Phone: 966-4035
Time:  Tuesday/Thursdays 10-11:20 am.
Classroom:  Fifth floor Agriculture Computer Lab

EVSC 421.3
Contaminated Site Management and Remediation
Steven D Siciliano
Office: 5E26 Agriculture
Phone: 966-4035
Time:  Tuesday/Thursdays 11:30-13:00

TOX 300.3 - 1(3L)
General Principles of Toxicology

An introduction to the general principles of toxicology. Salient topics include: dose-response relationships, toxicokinetics, target toxicity, mechanisms of toxic action, general principles of toxicity testing, and mechanisms of action of antidotes.

Prerequisite(s): (BMSC or BIOL 224 or BIOL 217) and BIOL 318.

TOX 301.3 - 1/2(3L)
Environmental Toxicology

A discussion of major environmental pollutants, their sources, interactions with atmospheric, terrestrial and aquatic systems, exposure of people, animals and other biota, and their dose-response relationships. Some of the physical and chemical changes induced in the environment by pollutants, contaminant fate and transport, and bioremediation are also discussed.

Prerequisite(s): BIOL 120 and 121 and CHEM 112.

TOX 310.3 - 1/2(3L-2T)
Radiation and Radionuclide Toxicology

Discusses natural and artificially produced radionuclides, units of radiation measurement, processes of decay and fission, interaction of radiation with matter, doses, risks of effects, and radionuclide transfer through ecosystems. Provides students with the knowledge to assess potential environmental impacts and health hazards from exposure to ionizing radiation from natural background, uranium mining and medical courses. A 2 hour tutorial once a week is included.

Prerequisite(s): BIOL 120 and 121 and CHEM 112 or PHYS 115.

TOX 302.3 - 1/2 (3L)
Introduction to Aquatic Toxicology

This course will provide an overview of the sources, fate and effects of toxicants in the aquatic environment. Material will center around prevailing issues reported in the popular news media associated with modern and legacy contaminants, and will illustrate how laboratory and field testing can be combined to assess and predict effects on organisms.  

Prerequisite(s): BIOL 120.3, BIOL 121.3 and CHEM 112.3.

TOX 320.3 - 1/2(3L)

Inhalation and Environmental Toxicology of Air Pollutants

Covers the sources, types, behavior and toxic effects of major air pollutants. It is based on four units: 1) atmospheric structure, evolution, energy balance and circulation; 2) major classes of air pollutants (including indoor air quality concerns), environmental behavior and effects; 3) the respiratory system as a target for toxic agents, mechanisms of damage and repair, assessment of respiratory function and standardized inhalation toxicity testing; and 4) students debates on current topics in air pollution and inhalation toxicology.

Prerequisite(s): BIOL 120.3, BIOL 121.3, CHEM 112.3, and CHEM 115.3.

TOX 321.3 - 1/2(3L)
Risk Assessment and Regulatory Toxicology

An introduction to human health and ecological risk assessment and an overview of Canadian and international regulatory requirements for the registration of new products, focusing on safety assessment/toxicity testing of pesticides and human pharmaceuticals, and basic principles of occupational health and industrial hygiene.

Prerequisite(s): 6 credit units BIOL and 6 credit units CHEM.
Note: TOX 300 and TOX 301 recommended.

TOX 400.3 - 1 (3L)
Quantitative Toxicology

This course provides students with the knowledge and tools required to design, evaluate and interpret toxicological studies. Students will learn how to identify putative causes of adverse effects, design experiments to evaluate these causes and how to estimate, and communicate about, how toxicant concentrations are linked to adverse effects. The course will include test designs at the organism, population and ecological levels of organization by using examples drawn from human and ecological toxicological disciplines. At the conclusion of this course, students will have gained an understanding of how human and ecological toxicity tests are designed, interpreted and communicated.

Prerequisite(s): TOX 300, TOX 301; and one of STAT 245, STAT 246 or PLSC 214

TOX 403.3 - 1/2(3L)
Biotoxins

An overview of the occurrence, mechanisms of action and clinical effects of commonly encountered plant toxins, mycotoxins, poisonous mushrooms, algal toxins, bacterial toxins, and zootoxins (venomous and poisonous snakes, fish, arthropods, and marine invertebrates).

Prerequisite(s): TOX 300 or permission of instructor.

TOX 412.3 - 1/2(3L)
Toxicology of Industrial Pollutants

An introduction to major categories, sources, routes of exposure, metabolism, mechanisms of action and toxic effects on people and ecosystems of common industrial organic chemicals, pesticides and metals. Emphasis will be placed on pollutants and industries of relevance to Canada.

Prerequisite(s): TOX 300.
Note: TOX 301 recommended.

TOX 461.3 - 1/2(1L-2S/T)
Applied Toxicology

Provides students an opportunity to evaluate practical toxicology/ecotoxicology problems associated with Saskatchewan and northern ecosystems. Students will be presented with specific toxicological questions or case studies of current relevance which will be examined using research data and library facilities. Written and oral presentations will be required for each problem.

Prerequisite(s): TOX 300 and 301.

TOX 480.3 - 1/2(6P)
Toxicology Research

Students will work on a laboratory, field, library, or theoretical study under the supervision of a faculty member from the Toxicology Group. Each individual project requires approval of a research proposal by the Toxicology Program Chair in the term preceding registration before permission will be granted. A thorough, written report in thesis format describing the project and the summarized results submitted at the end of the project will be evaluated by the supervisor.

Permission of the department required.
Prerequisite(s): TOX 300 and 301.
Note: Students with credit for TOX 481 may not take this course for credit.  This course is only open to Honours students in the fourth year of their Toxicology program, unless special permission has been granted by the Toxicology Program Chair.

TOX 481.6 - 1&2(6P)
Toxicology Research

Students will work on a toxicology research project under the supervision of a faculty member from the Toxicology Group. Each project requires approval of a research proposal by the Toxicology Academic Advisor prior to registration. A written report in thesis format must be submitted at the end of the project.

Permission of the department required.
Prerequisite(s): TOX 300 and 301.
Note: Students with credit for TOX 480 may not take this course for credit. This course is only open to Honours students in the fourth year of their Toxicology program, unless special permission has been granted by the Toxicology Program Chair.

TOX 490.0 - 1&2(1S)
Toxicology Seminar

Seminar presentations by visitors, faculty and students on a broad selection of toxicology issues. Fourth-year students in the Undergraduate Toxicology Program will be required to present one seminar and attend all seminars throughout the full academic year.

Prerequisite(s): TOX 300 and 301.

GEOG 386.3 - 1/2(3L)
Environmental Impact Assessment

A practical and theoretical introduction to environmental and socioeconomic impact assessment. Emphasis is placed on the principles and characteristics of impact assessment as set out under Canadian and Saskatchewan guidelines and legislation, and on the lessons learned from selected case studies.

Prerequisite(s): GEOG 280 or permission of the instructor.

BIOL 475.3 - 1/2(3L-3P)
Ecological Toxicology

An introduction to the principles of ecological toxicology, including: population modeling, experimental design and interpretation of field studies, and contaminant impact assessment on populations, communities and ecosystems. Computer laboratory exercises will be used to model populations and ecosystems and analyze changes in populations and communities resulting from contaminant impacts.

Prerequisite(s): BIOL 120 and 121 and BIOL 228 and 6 additional credit units of senior BIOL courses and a course in statistics; or permission of the instructor.
Note: TOX 301 is recommended.

EVSC 420.3 - 1(3L)
Environmental Fate and Transport of Toxic Substances

In this lecture/practicum based course, students will learn how to construct a multi-media environmental model using freely available software. Students will be exposed to the fundamental theory of environmental fate modeling with a focus on how contaminant movement and transformation in the atmosphere, hydrosphere, biosphere and geosphere are incorporated into long term environmental fate models. The course is located in a computer lab and the emphasis is on practical construction, implementation and interpretation of fugacity based environmental fate models. Each lecture period consists of a brief theoretical overview followed by application and implementation of the equations into the students fate model.

Prerequisite(s): MATH 104 or 110; PHYS 115 or EVSC 210; successful completion of 60 credit units of university level courses.

EVSC 421.3 - 1/2(1L-3P)
Contaminated Site Management and Remediation

This course will focus on how contaminated sites are managed and remediated for new land uses. Students will learn the theory of how sites are investigated and characterized, how toxicological information is used to estimate the risk to humans and ecosystems, how threats to groundwater are assessed and finally, methods by which these risks and threats are mitigated through remediation approaches. This course will provide students with the skill sets necessary to assess, manage and reduce human and ecological risk at a contaminated site. 

Prerequisite(s): EVSC 210 or 3 credit units 100-level PHYS, STAT 245 or PLSC 314, and one of EVSC 220, SLSC 240 or RRM 215.
Prerequisite(s) or Corequisite(s): One of TOX 321, GEOG 386, BLE 481, SLSC 313 or SLSC 322.