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Publications

1)
Zhang, X., Newsted, J.L, Hecker, M.,  Higley, E., Jones, P. D.,  Giesy, J. P.  (2009). Classification of Chemicals Based on Concentration-Dependent Toxicological Data Using "ToxClust©" Environ. Sci. Technol. 43 (10), 3926–3932. PDF

 

2)
Gracia, T., Lam, P.K.S., Wu, R.S.S., Giesy, J.P., Jones, P.D., Higley, E.B., Hilscherova, K., Hecker, M.
Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay
(2008) Environmental Science and Pollution Research, 15 (4), pp. 332-343. PDF

 

3)
Song, R., Wu, R.S.S., Zhang, W., Sheng, G., Fu, J., He, Y., Murphy, M.B., Giesy, J.P.
Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line
(2008) Chemosphere, 71 (10), pp. 1888-1894. PDF

 

4)
He, Y., Murphy, M.B., Yu, R.M.K., Lam, M.H.W., Hecker, M., Giesy, J.P., Wu, R.S.S., Lam, P.K.S.
Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line
(2008) Toxicology Letters, 176 (3), pp. 230-238. PDF

 

5)
Hecker, M., Giesy, J.P.
Novel trends in endocrine disruptor testing: The H295R Steroidogenesis Assay for identification of inducers and inhibitors of hormone production
(2008) Analytical and Bioanalytical Chemistry, 390 (1), pp. 287-291. PDF

 

6)
Gracia, T., Lam, P.K.S., Wu, R.S.S., Giesy, J.P., Hilscherova, K., Jones, P.D., Newsted, J.L., Yu, R.M.K.
Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds
(2007) Toxicology and Applied Pharmacology, 225 (2), pp. 142-153. PDF

 

7)
Hecker, M., Wu, R., Lam, P., Laskey, J., Buckalew, A., Grund, S., Nakai, M., Newsted, J.
The OECD validation program of the H295R Steroidogenesis Assay for the identification of in vitro inhibitors and inducers of testosterone and estradiol production. Phase 2: Inter-laboratory pre-validation studies
(2007) Environmental Science and Pollution Research, 14 (1), pp. 23-30. PDF

 

8)
Hecker, M., Newsted, J.L., Murphy, M.B., Higley, E.B., Jones, P.D., Wu, R., Giesy, J.P.
Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: Hormone production
(2006) Toxicology and Applied Pharmacology, 217 (1), pp. 114-124. PDF

 

9)
Zhang, X., Wu, R.S.S., Giesy, J.P., Yu, R.M.K., Jones, P.D., Lam, G.K.W., Newsted, J.L., Sanderson, J.T.
Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line
(2005) Environmental Science and Technology, 39 (8), pp. 2777-2785. PDF

 
10)
Hilscherova, K., Jones, P.D., Gracia, T., Newsted, J.L., Zhang, X., Sanderson, J.T., Yu, R.M.K., Giesy, J.P.
Assessment of the effects of chemicals on the expression of ten steroidogenic genes in the H295R cell line using real-time PCR
(2004) Toxicological Sciences, 81 (1), pp. 78-89. PDF
 
Last updated October 1st, 2009