Hiebert, Linda


Linda Hiebert

Department of Veterinary Biomedical Sciences
52 Campus Drive
Saskatoon, Saskatchewan, Canada
S7N 5B4

Phone: (306) 966-7358

Email: linda.hiebert@usask.ca

Academic Degrees

B.A., M.Sc., Ph.D. (Saskatchewan)

Current Teaching

  • TOX 836.5 General Toxicology I (Toxicokinetics section of team taught course)
  • TOX 837.5 General Toxicology II (Cardiovascular Toxicology section of team taught course)
  • VBMS 221.8 Physiology I (Course Coordinator, Cardiovascular section of team taught course)
  • VBMS 834.6 Physiology I (Cardiovascular section of team taught course)
  • VBMS 324.3 Animal Physiology I (Haematology, Cardiovascular section of team taught course)
  • BIOL 217.3 Introductory Animal Physiology (Neurophysiology and Special Senses section of team taught course)

Current and Recent Research Projects

  • Toxic effects of polonium-210 alpha radiation on human and animal systems using models of bovine, porcine and human endothelial cells, and bovine pulmonary epithelial cells.
  • Endothelial dysfunction in hypertension and diabetes.
  • Endothelial dysfunction associated with free radical injury.
  • βFGF activity and heparan sulphate depletion associated with diabetic microvascular complications.
  • The role of heparanase.
  • Studies in endothelial cell cultures and in a rat model of hyperglycemia.
  • Pharmacodynamic and pharmacokinetic studies of oral heparins and related glycosaminoglycans.


Thomas, P., B. Tracy, T. Ping, M.. Wickstrom, N. Sidhu and L. Hiebert.  2003.  Relative biological effectiveness (RBE) of polonium-210 alpha-particles vs. X-rays on lethality in bovine endothelial cells.  Int. J. Radiat. Biol. 79(2): 107-118.

Hiebert, L.M.  2002.  Oral heparins.  Clin. Lab. 48: 111-116.

Hiebert, L.M., S.M. Wice, T. Ping, R.E. Hileman, T. Polat and R.J. Linhardt.  2002.  Tissue distribution of [14C] sucrose octasulfate following oral administration to rats.  Pharmaceut. Res. 19(6): 838-844.

Ram, J.I. and L.M. Hiebert.  2001.  Marked variation in free radical injury between bovine and porcine endothelial cells cultured in different medium.  In Vitro Mol. Toxicol. 14(3): 209-217.

Hiebert, L.M., S.M. Wice, T. Ping, D. Herr and V. Laux.  2001.  Antithrombotic efficacy of the low molecular weight heparin, reviparin sodium, administered by the oral route.  Thromb. Haemostasis 85: 114-118.