Weber, Lynn

Associate Professor

Lynn Weber

Department of Veterinary Biomedical Sciences
WCVM 1319, 51 Campus Drive
Saskatoon, Saskatchewan, Canada
S7N 5B4

Phone: (306) 966-8734

Email: lynn.weber@usask.ca


Academic Degrees

  • BSc, Pharmacy, University of British Columbia
  • PhD, Pharmacology & Toxicology, University of British Columbia
  • Post-doctoral Fellow, Smooth Muscle Research Group, University of Calgary
  • Post-doctoral Researcher, Zoology, Oklahoma State University

Current Teaching

Dr. Weber's main teaching responsibility is VBMS 224 (Veterinary Physiology) which is the core physiology course for veterinary students. The course includes sections of basic cellular, neural, muscle and hematological physiology. She also teaches in VBMS 333 (General Pharmacology), covering sections on autonomic, cardiac and diuretic pharmacology. She teaches a core toxicology graduate course VBMS 855 (Integrative Cardiovascular Physiology & Toxicology) and contributes sections to several other graduate toxicology courses in cardiovascular physiology and environmental toxicology.


Current and Recent Research Projects

Dr. Weber's main research theme is on the effect of environmental influences on the cardiovascular system. In particular, she is interested in the interaction of toxicants, nutrition and climate change on cardiovascular and metabolic in mammals and fish.

These are her current research projects:

  • Interaction between polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor with cardiac and metabolic responses to thermal challenges in fish. 
  • Effects of metal mining effluents on fish larval development, metabolic health and performance.
  • Dog and cat nutrition studies examining the effects of glycemic index, obesity and the toxic glucose metabolite, methylglyoxal, on cardiovascular and metabolic health. 
  • Mechanisms of cardiometabolic effects of vitamin D deficiency and toxicity.

Publications

Arcand, S., Sharma, K., Al-Dissi, A.N., Cadete, V.J.J., Sawicki, G., Weber, L.P. 2013. Resveratrol protects against functional impairment and cardiac structural protein degradation induced by second hand smoke exposure. Canadian Journal of Cardiology 29, 1320-1328.

Adolphe, J.L., Silver, T.I., Childs, H., Drew, M.D., Weber L.P. 2014. Short-term obesity results in detrimental metabolic and cardiovascular changes that may not be reversed with weight loss. British Journal of Nutrition. 112, 647-656.

Gerger, C.J., Thomas, J.K., Janz, D.M., Weber, L.P. 2015. Affects of acute β-naphthoflavone on cardiorespiratory function and metabolism in adult zebrafish (Danio rerio). Fish Physiology & Biochemistry 41, 289-298 DOI 10.1007/s10695-014-9982-z.

Adolphe, J.L., Drew, M.D., Silver, T.I., Fouhse J., Childs, H., Weber L.P. 2015. Effect of an extruded pea or rice diet on post-prandial insulin responses and cardiovascular health in obese dogs. Journal ofAnimal Physiology & Animal Nutrition DOI: 10.1111/jpn.12275.

Wildemann, T.M., Weber, L.P., Siciliano, S.D. 2015. Combined exposure to lead, inorganic mercury and methylmercury shows deviation from additivity for cardiovascular toxicity in rats.  Journal of Applied ToxicologyDOI 10.1002/jat.3092.

Wildemann, T.M., Mirhosseini, N.M., Siciliano, S.D., Weber, L.P. 2015. Cardiovascular responses to lead are biphasic, while methylmercury, but not inorganic mercury, monotonically increases blood pressure in rats. Toxicology 328, 1-11 DOI 10.1016/j.tox.2014.11.009.

Gerger, C.J., Weber, L.P. 2015. Comparison of the acute effects of benzo-a-pyrene on adult zebrafish (Danio rerio) cardiorespiratory function following intraperitoneal injection versus aqueous exposure. Aquatic Toxicology 165, 19-30. DOI 10.1016/j.aquatox.2015.05.008.

Wildemann, T.M., Siciliano, S.D., Weber, L.P. 2016. The mechanisms associated with development of hypertension after exposure to lead,  mercury species or their mixtures differs with the metal and the mixture ratio. Toxicology 339, 1-8 DOI 10.1016/j.tox.2015.11.004.