Niyogi, Som

Associate Professor

Som Niyogi

Department of Biology
University of Saskatchewan, 112 Science Place
Saskatoon, Saskatchewan, Canada
S7N 5E2

Phone: (306) 966-4453


Academic Degrees

  • M.Sc. (Calcutta), Ph.D. (Calcutta)

Current Teaching

  • BIOL 121.3 The Diversity of Life
  • BIOL 224.3 Animal Body Systems
  • TOX 301.3 Environmental Toxicology
  • BIOL 898.3 Physiological Toxicology of Aquatic Animals

Current and Recent Research Projects

  • Physiological and molecular mechanisms of uptake, homeostasis and toxicity of trace metals in freshwater fish
  • Application of the Biotic Ligand Model (BLM) approach in assessing bioavailability and toxicity of metals/metal-mixtures to freshwater fish
  • Population level effects of industrial metal pollution in freshwater fish: Influence of toxicity modifying factors


J.D. Ouellet, M.G. Dube, S. Niyogi. 2013. The influence of elevated alkalinity and natural organic matter (NOM) on tissue-specific metal accumulation and reproductive performance in fathead minnows during chronic, multi-trophic exposures to a metal mine effluent. Ecotoxicology and Environmental Safety 95, 104-112.

J.D. Ouellet, M.G. Dube, S. Niyogi. 2013. The influence of food quantity on metal bioaccumulation and reproduction in fathead minnows (Pimephales promelas) during chronic exposures to a metal mine effluent. Ecotoxicology and Environmental Safety 91, 188-197.

J.D. Ouellet, M.G. Dube, S. Niyogi. 2013. A single metal, metal mixture, and whole-effluent approach to investigate causes of metal mine effluent effects on fathead minnows (Pimephales promelas). Water, Air, & Soil Pollution 224(3), 1-19.

R.W. Kwong, C. Hamilton, S. Niyogi. 2013. Effects of elevated dietary iron on the gastrointestinal expression of Nramp genes and iron homeostasis in rainbow trout (Oncorhynchus mykiss). Fish Physiology and Biochemistry 39, 363-372.

S. Misra, R.W. Kwong, S. Niyogi. 2012. Transport of selenium across the plasma membrane of primary hepatocytes and enterocytes of rainbow trout. Journal of Experimental Biology 215, 1491-1501.

S. Misra, C. Hamilton, S. Niyogi. 2012. Induction of oxidative stress by selenomethionine in isolated hepatocytes of rainbow trout (Oncorhynchus mykiss). Toxicology in Vitro 26, 621-629.

S. Misra, D. Peak, N. Chen, C. Hamilton, S. Niyogi. 2012. Tissue-specific accumulation and speciation of selenium in rainbow trout (Oncorhynchus mykiss) exposed to elevated dietary selenomethionine. Comparative Biochemistry and Physiology Part C 155, 560-565.

A.K. Manek, M.C. Ferrari, J.M. Sereda, S. Niyogi, D.P. Chivers. 2012. The effects of UV radiation on a freshwater prey fish: physiological stress response, club cell investment and alarm cue production. Biological Journal of the Linnean Society 105, 832-841.

R.W. Kwong, S. Niyogi. 2012. Cadmium transport in isolated enterocytes of freshwater rainbow trout: interactions with zinc and iron, effects of complexation with cysteine, and an ATPase-coupled efflux. Comparative Biochemistry and Physiology Part C 155, 238-246. 

L.D. Rozon-Ramilo, M.G. Dube, A.J. Squires, S. Niyogi. 2011. Examining waterborne and dietborne routes of exposure and their contribution to biological response patterns in fathead minnow (Pimephales promelas). Aquatic Toxicology 105, 466-481.

J.C. McGeer, S. Niyogi, D.S. Smith. 2011. Cadmium. In Homeostasis and Toxicology of Non-Essential Metals: FISH PHYSIOLOGY Volume 31B. pp. 125-184. C.M. Wood, A.P. Farrell and C.J. Brauner (Eds). Elsevier.

L.D. Rozon-Ramilo, M.G. Dube, C.J. Rickwood, S. Niyogi. 2011. Examining the effects of metal mining mixtures on fathead minnow (Pimephales promelas) using field-based multi-trophic artificial streams. Ecotoxicology and Environmental Safety 74, 1536-1547.

R.W. Kwong, J.A. Andrés, S. Niyogi. 2011. Effects of dietary cadmium exposure on tissue-specific cadmium accumulation, iron status and expression of iron-handling and stress-inducible genes in rainbow trout: Influence of elevated dietary iron. Aquatic Toxicology 102, 1-9.

Selected Publications (2004-2010)

R.W. Kwong, J.A. Andrés, S. Niyogi. 2010. Molecular evidence and physiological characterization of iron absorption in isolated enterocytes of rainbow trout (Oncorhynchus mykiss): Implications for dietary cadmium and lead absorption. Aquatic Toxicology 99, 343-350.

S. Misra, D. Peak, S. Niyogi. 2010. Application of XANES spectroscopy in understanding the metabolism of selenium in isolated rainbow trout hepatocytes: insights into selenium toxicity. Metallomics 2, 710-717.

S. Misra, S. Niyogi. 2009. Selenite causes cytotoxicity in rainbow trout (Oncorhynchus mykiss) hepatocytes by inducing oxidative stress. Toxicology in Vitro 23, 1249-1258.

R.W. Kwong, S. Niyogi. 2009. The interactions of iron with other divalent metals in the intestinal tract of a freshwater teleost, rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology Part C 150, 442-449.

S. Niyogi, R. Kent, C.M. Wood. 2008. Effects of water chemistry variables on gill binding and acute toxicity of cadmium in rainbow trout (Oncorhynchus mykiss): A biotic ligand model (BLM) approach. Comparative Biochemistry and Physiology Part C 148, 305-314.

R.W. Kwong, S. Niyogi. 2008. An in vitro examination of intestinal iron absorption in a freshwater teleost, rainbow trout (Oncorhynchus mykiss). Journal of Comparative Physiology 178B: 963-975.

S. Niyogi, G.G. Pyle, C.M. Wood. 2007. Branchial versus intestinal zinc uptake in wild yellow perch (Perca flavescens) from reference and metal-contaminated aquatic ecosystems. Canadian Journal of Fisheries and Aquatic Sciences 64, 1605-1613

S. Niyogi, C. Kamunde, C.M. Wood. 2006. Food selection, growth and physiology in relation to dietary sodium chloride content in rainbow trout (Oncorhynchus mykiss) under chronic waterborne copper exposure. Aquatic Toxicology 77, 210-221.

S. Niyogi, C.M. Wood. 2004. The Biotic Ligand Model, a flexible tool for developing site-specific water quality guidelines for metals. Environmental Science and Technology 38, 6177-6192.

S. Niyogi, C.M. Wood. 2004. Kinetic analyses of waterborne calcium and cadmium transport and their interactions in the gills of rainbow trout (Oncorhynchus mykiss) and yellow perch (Perca flavescens), two fish species differing greatly in acute cadmium sensitivity. Journal of Comparative Physiology 174B, 243-253.