Immunology and Infectious Diseases
Scientists at the Western College of Veterinary Medicine
and the University of Saskatchewan have played primary and collaborative roles
in the identification, treatment and prevention of diseases such as neonatal
calf diarrhea, post weaning multi-systemic wasting syndrome (PMWS) in pigs,
chronic wasting disease, West Nile virus, and bovine respiratory disease.
The College's close links to infectious disease and
immunology research have sparked the development of specialized centres like
the Vaccine and Infectious Disease Organization (VIDO) and the Canadian
Cooperative Wildlife Health Centre - an academic wildlife health sciences
institute among Canada's five veterinary colleges.
Collaborations with these organizations - plus
partnerships with the U of S College of Medicine, provincial and federal
government agencies and other national research centres have led to the
involvement of WCVM faculty and graduate students in various projects targeting
infectious disease- and immunology-related issues in domestic animals, wildlife
and humans. The collaborative work has also led to the development of the U of
S Immunology and Infectious Diseases Research Group - a cross-campus
WCVM faculty members continue to be involved in
a wide range of projects that focus on immunology and infectious diseases. New
treatments for bovine pneumonic pasteurellosis (shipping fever) and mastitis
lesions, the role of pulmonary intravascular macrophages (PIMs) in lung inflammation,
the humoral innate immune defenses in porcine milk and porcine circovirus type
2 studies are some examples of ongoing projects. As well, WCVM scientists are
involved in investigations of infectious diseases in poultry, specialized
livestock, companion animals, wildlife, horses and people.
- Chirino-Trejo, Manuel
veterinary bacteriology/mycology in domestic and wild animals as well as monitoring
of antimicrobial drug resistance in pathogenic bacteria of domestic animals.
- Ellis, John
Canine infectious tracheobronchitis; particularly immunity to Bordetella bronchiseptica. Neonatal immunization of calves; particularly early immunization for bovine respiratory syncytial virus. Porcine circo and torqueteno viruses; pathogenesis and vaccine development.
- Gerdts, Volker
Development of neonatal vaccines; innate immunity at the respiratory surfaces (antimicrobial peptides); basic mechanisms of intestinal immunity; lymphocyte trafficking; mucosal immunology; chemokines; enteric infections; and knowledge transfer of basic research into applied clinical research and producers.
- Gordon, John
Immunology and immunopathology, particularly examining allergic disease and inflammation.
- Griebel, Philip
Immunology and viral pathogenesis.
- Haines, Deborah
The study of the occurrence and prevention of failure of passive transfer of maternal antibody in cattle; immunohistochemical and rapid methods for diagnosis of immunodeficiencies, immune-mediated diseases, tumors and infectious diseases.
- Harding, John
Swine health including investigations of porcine circovirus type 2 (PCV2), and the effects of fetal programming on fetal immunology and post-natal health of swine.
- Jenkins, Emily
Public health and food safety including involvement in studies looking at the circulation of diseases between dogs, wildlife and people in the North.
- Koester, Wolfgang
Various aspects of food and water safety, virulence mechanisms of pathogenic bacteria and host-pathogen interactions.
- Kryworuchko, Marko
- Liu, Qiang
Elucidating molecular mechanisms of viral pathogenesis. Special research areas are human hepatitis viruses (such as hepatitis C virus) and porcine circoviruses.
- Montgomery, Julia
- Potter, Andrew
Application of genomics to the animal health field. Dr. Potter's work also focuses on forging links between the animal and human infectious disease research communities to ensure that technologies common to both fields can be leveraged to their greatest benefit.
- Simko, Elemir
Various aspects of comparative innate immunity, pathogenesis of infectious diseases and evidence-based diagnostic anatomic pathology of vertebrate species.
- Singh, Baljit
Cell and molecular biology of lung inflammation. Dr. Singh's projects focus on mechanisms of neutrophil and monocyte migration into inflamed lungs, biology of pulmonary intravascular macrophages and environmental pulmonary toxicology.
- Townsend, Hugh
Infectious disease epidemiology, vaccine formulation, delivery and efficacy; and the immune response to infection. Dr. Townsend's recent research focuses on the investigation of a foal's immune response and its susceptibility to Rhodococcus equi pneumonia.
- Zhou, Yan
Molecular biology, pathogenesis and vaccine development of influenza virus.