University of Saskatchewan

Western College of Veterinary Medicine


Translational Research Models

The Western College of Veterinary Medicine is a key component of the University of Saskatchewan's life sciences research and training cluster of colleges. The concept of "One world, one health, one medicine" is reflected in the College's integrated plan, and it's an approach that the veterinary college is building on to create more connections between animal health, human health and ecosystem health.

Throughout its history, WCVM researchers have been highly effective in using models of anatomy, physiology, disease or drug therapies, research teams to make valuable advances in animal and human health. For example, WCVM faculty members have developed translational research models in areas such as reproduction where bovine models have helped scientists learn more about ovarian function and follicular dynamics in both animals and humans.  Researchers are also learning more about the manipulation of spermatogenesis for human therapies through the use of animal models.

In the area of neurophysiology, rat models are helping research teams learn more about the effects of central nervous system disease or injury on the sensorimotor behaviour of humans as well as animals. Testing the effectiveness of antithrombotic drugs, such as heparin, in dogs is helping scientists learn more about their pharmocodynamics and use in humans. In the area of infectious diseases, an intensive investigation of West Nile virus in horses helped to shed light on the disease's epidemiology in Western Canada.

In the area of environmental toxicology, swine, fish and canine models are helping researchers learn more about the effect of environmental toxicants on the cardiovascular system. Translational research models are also highly effective in the areas of ophthalmology and oncology where human and veterinary scientists can equally gain fresh perspectives on the pathogenesis of disease as well as treatment, early detection and prevention.

Veterinary medical oncology: treatment research