Dr. Rubin's research focuses on the theme of antimicrobial resistance. Before the introduction of penicillin as a drug in the early 1940's physicians were largely powerless to bacterial infections; antibiotics were arguably the most important advance in medicine of the 20th century. Unfortunately, the extraordinary ability of bacteria to adapt led to the emergence of antibiotic resistance. Resistant organisms, commonly called 'superbugs', are increasingly encountered in both human and veterinary medicine and are threatening the ability of physicians and veterinarians to treat their patients. Many of these bacteria are well adapted to a wide variety of hosts, and easily transmit between humans and animals making antibiotic resistance a problem for both human and veterinary medicine.
Dr. Rubin's research spans the following topics:
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