Veterinary Biomedical Sciences
Office Location: WCVM 1319
- BSc, Pharmacy, University of British Columbia
- PhD, Pharmacology & Toxicology, University of British Columbia
- Post-doctoral Fellow, Smooth Muscle Research Group, University of Calgary
- Post-doctoral Researcher, Zoology, Oklahoma State University
Teaching and Clinical Areas
Dr. Weber's main teaching responsibility is VBMS 224 (Veterinary Physiology) which is the core physiology course for veterinary students. The course includes sections of cell biology, muscle and cardiovascular physiology. She also teaches in VBMS 333 (General Pharmacology), covering sections on autonomic, cardiac and diuretic pharmacology. She teaches a graduate course VBMS 855 (Integrative Cardiovascular Physiology & Toxicology) and contributes sections to several other graduate courses in cardiovascular physiology and environmental toxicology.
Dr. Weber's main research focus is on the effect of environmental influences, primarily toxicants and nutritional factors, on the cardiovascular system. In particular, she is interested in the interaction of toxicants with genes via nuclear receptors to produce alterations in development and function of the cardiovascular system in mammals and fish. These are her current research projects:
- Influence of vitamin D deficiency and excess on cardiovascular health.
- How glycemic index, obesity and diabetes negatively interact to negatively affect cardiovascular health.
- Role of polycyclic aromatic hydrocarbons (PAHs) in tobacco smoke-induced vascular dysfunction.
- Interaction of genes and the environment with the aryl hydrocarbon receptor and fish cardiovascular function.
- Effects of metal mining effluents on fish larval development and performance.
- Arcand, S., Sharma, K., Al-Dissi, A.N., Cadete, V.J.J., Sawicki, G., Weber, L.P. (2013) Resveratrol protects against functional impairment and cardiac structural protein degradation induced by second hand smoke exposure. Canadian Journal of Cardiology doi.org/10.1016/j.cjca.2013.04.030.
- Manek, A.K., Ferrari, M.C.O., Pollock, R.J., Vicente, D., Weber, L.P., Chivers, D.P. (2013) Within and between population variation in epidermal club cell investment in a freshwater prey fish: a cautionary tale for evolutionary ecologists. PLOS ONE 8(3), e56689.
- Gentner, N.J., Weber, L.P. (2012) Environmental tobacco smoke, arterial stiffness and altered circadian blood pressure patterns are associated with lung inflammation and oxidative stress. American Journal of Physiology 302, H818-H825.
- Adolphe, J.L., Drew, M.D., Huang, Q., Silver, T., Weber, L.P. (2012) Post-prandial impairment of flow-mediated dilation and elevated methylglyoxal after simple, but not complex, carbohydrate consumption in dogs. Nutrition Research 32, 278-284.
- Marit, J.S., Weber, L.P. (2012) Persistent effects on adult swim performance and energetics in zebrafish developmentally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Aquatic Toxicology 106-107, 131-139.
- Goertzen, M.M., Hauck, D.W., Phibbs, J., Weber, L.P., Janz, D.M. (2012) Swim performance and energy homeostasis in spottail shiner (Notropis hudsonius) collected downstream of a uranium mill.Ecotoxicology & Environmental Safety 75, 142-150.