Structure and Function of Biomolecules 2(3L) Prerequisite(s): CHEM 242, 255; BIOC 230, 310. One of either CHEM 255 or BIOC 230 may be taken concurrently.
Introduces the underlying properties that dictate the folding, structure and stability of biological macromolecules and how these ultimately affect function. This is a lecture-based course that will focus on advanced principles and properties of macromolecular structure, their relationship to thermodynamic principles of equilibrium and stability, and biological activity.
Provides an introduction to a number of techniques that are commonly used for studying biological macromolecules. This is a laboratory course to complement the knowledge gained in BMST 305. Students will become familiar with various biophysical techniques for studying biomolecular properties and activities.
BMST 408.3
Macromolecular Structure Determination 2(3L) Prerequisite(s): CHEM 353 and BMST 305.
Provides students with a basic understanding of techniques used to probe the structures of macromolecules. The core focus of the course will be X-ray crystallography and nuclear magnetic resonance spectroscopy (NMR) with applications to protein and nucleic acid structure determination. Cryo-electron microscopy will also be discussed.
BMST 485.6
Research in Biomolecular Structure Studies 1/2(8-9 hours P) Prerequisite(s): BMST 406 and 408.
Students will work on a research project for two terms in the laboratory of a faculty member that is actively involved in structure-based studies of biomolecules. They will gain experience in experimental procedures, data analysis, and preparation of both a written report and oral presentation on their scientific findings.